After establishing Boonesborough, one of the first settlements west of the Appalachian Mountains, legendary frontiersman Daniel Boone finds his new settlement at war with the Shawnee. To survive, they must leave the fort to find salt to preserve their meat through the winter. Leaving his family behind, Boone guides a small company on a 60-mile journey to the nearest salt lick. But before they can finish their work, the men are ambushed by a Shawnee war party on the way to attack Boonesborough. Somehow, Boone persuades the Chief to postpone attacking the fort in exchange for the surrender of the men harvesting the salt. While being held as a captive, Boone hatches a plan to escape and travel 160 miles through hostile territory to warn Boonesborough, and his family, of the impending attack.